Hull dropped into the relegation zone as they suffered a first home defeat under Marco Silva against relegated Sunderland.
The hosts created several chances, only for Lazar Markovic and Abel Hernandez - most notably - to be denied by impressive away keeper Jordan Pickford.
Sunderland took advantage to go ahead through Billy Jones'' close-range diving header after John O''Shea''s flick-on from a corner.
And the Black Cats sealed their first win in 11 league matches when Jermain Defoe converted from close range.
Hull fell to 18th place after Swansea beat Everton 1-0 later on Saturday to move one point above the Tigers.
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